Early physiologic responses to hemorrhagic hypotension

Systemic responses to prolonged hemorrhagic hypotension.

Studies are needed to provide a rigorous examination of the relevance of monitored variables during prolonged hemorrhagic hypotension (HH). This study was designed to investigate the parameters that describe biochemical and O2 transport patterns in animals subjected to HH. Systemic parameters that could differentiate survivors from nonsurvivors were identified. An aortic flow probe was implante...

Long Term Hypoxia Alters Ovine Fetal Endocrine and Physiologic Responses to Hypotension

Cardiovascular Effect of Cuneiform Nucleus During Hemorrhagic Hypotension

Introduction: The underlying mechanism responsible for the cardiovascular response to hemorrhage (HEM) is still unknown; however, several brain areas, such as the cuneiform nucleus (CnF) have shown to be involved. In this study, the cardiovascular effect of the CnF during HEM was evaluated. Methods: The animals were divided into the following groups: 1. Vehicle; 2. HEM; 3. Cobalt chloride (CoC...

Pressor effect of electroacupuncture on hemorrhagic hypotension.

Neiguan (PC-6) is a traditional acupoint in each forearm and overlies the trunk of the median nerve. Previous studies show that electroacupuncture (EA) at the Neiguan acupoint could improve not only myocardial ischemic dysfunction by inducing a depressor response but also recover hemorrhagic hypotension by inducing a pressor response. However, their physiological mechanisms are not yet elucidat...

Continuous peripheral resistance measurement during hemorrhagic hypotension.

We tested the hypotheses that continuous total peripheral resistance (TPR) measurements are superior to intermittent data collection and that variables related to TPR can be used to distinguish between survivors and nonsurvivors (NS), respectively, of prolonged hemorrhagic hypotension (HH). One week after a transit-time ultrasound probe was implanted on their ascending aortas, 21 rats were subj...